Securing the Eradication of All Polioviruses

Environmental surveillance for polioviruses in the Global Polio Eradication Initiative.

This article summarizes the status of environmental surveillance (ES) used by the Global Polio Eradication Initiative, provides the rationale for ES, gives examples of ES methods and findings, and summarizes how these data are used to achieve poliovirus eradication. ES complements clinical acute flaccid paralysis (AFP) surveillance for possible polio cases. ES detects poliovirus circulation in ...

Securing All-Optical Networks

All-optical networks (AONs) are a relatively new technology for high data-rate communications. They contain only optical components and are intrinsically different from optical networks currently being used. More specifically, AONs provide transparent features that allow routing and data switching without necessitating the interpretation or regression of signals within the network. Consequently...

Securing Safe Plasma for Fractionation the Duty of any Country

A Nested RT-PCR Method for Confirming the Absence of all Three Types of Polioviruses in Primates and Human Cells Used in Vaccine Production

No abstract this article: A Nested RT-PCR Method for Confirming the Absence of all Three Types of Polioviruses in Primates and Human Cells Used in Vaccine Production

Highly divergent neurovirulent vaccine-derived polioviruses of all three serotypes are recurrently detected in Finnish sewage.

In Finland, surveillance of potential re-emergence of poliovirus transmission is mainly based on environmental surveillance, i.e. search for infectious poliovirus in sewage samples. Since December 2008, 21 genetically highly divergent, neurovirulent vaccine-derived polioviruses (VDPV) have been isolated from sewage in Tampere, Finland. While the source of the VDPV is unknown, characteristics of...